Control of flagellar length in Chlamydomonas

Paul A. Lefebvre; Catherine M. Asleson; Lai Wa Tam

doi:10.1016/S1044-5781(06)80073-3

Control of flagellar length in Chlamydomonas

Paul A. Lefebvre, Catherine M. Asleson, Lai Wa Tam

Plant and Microbial Biology

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

The flagella of the unicellular green alga Chlamydomonas reinhardtii are controlled by a number of sophisticated homeostatic mechanisms which ensure that the flagella are maintained at a specific length, and that each cell has two flagella of equal length. Mutants with defects in flagellar length control have been obtained, defining at least nine genes that are involved in the control of flagellar length and the equality of flagellar length. The active machinery involved in flagellar length control requires that cells precisely measure the length of their flagella and drastically alter flagellar protein production and assembly when necessary to maintain desired lengths.

Original language	English (US)
Pages (from-to)	317-323
Number of pages	7
Journal	Seminars in Developmental Biology
Volume	6
Issue number	5
DOIs	https://doi.org/10.1016/S1044-5781(06)80073-3
State	Published - 1995

Bibliographical note

Funding Information:
Research in the Lefebvre laboratory was supported by a grant from the US Public Health Service (NIGMS 34437). C.M.A. was supported by a Research Training Group Grant BIR 9113444 from the National Science Foundation. L-W.T. was supported by a fellowship from the University of Minnesota Plant Molecular Genetics Institute, and by a National Research Service Award from the NIAID (F32 AI08942).

Keywords

Chlamydomonas
flagella
mutants

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title = "Control of flagellar length in Chlamydomonas",

abstract = "The flagella of the unicellular green alga Chlamydomonas reinhardtii are controlled by a number of sophisticated homeostatic mechanisms which ensure that the flagella are maintained at a specific length, and that each cell has two flagella of equal length. Mutants with defects in flagellar length control have been obtained, defining at least nine genes that are involved in the control of flagellar length and the equality of flagellar length. The active machinery involved in flagellar length control requires that cells precisely measure the length of their flagella and drastically alter flagellar protein production and assembly when necessary to maintain desired lengths.",

keywords = "Chlamydomonas, flagella, mutants",

author = "Lefebvre, {Paul A.} and Asleson, {Catherine M.} and Tam, {Lai Wa}",

note = "Funding Information: Research in the Lefebvre laboratory was supported by a grant from the US Public Health Service (NIGMS 34437). C.M.A. was supported by a Research Training Group Grant BIR 9113444 from the National Science Foundation. L-W.T. was supported by a fellowship from the University of Minnesota Plant Molecular Genetics Institute, and by a National Research Service Award from the NIAID (F32 AI08942).",

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AU - Lefebvre, Paul A.

AU - Asleson, Catherine M.

AU - Tam, Lai Wa

N1 - Funding Information: Research in the Lefebvre laboratory was supported by a grant from the US Public Health Service (NIGMS 34437). C.M.A. was supported by a Research Training Group Grant BIR 9113444 from the National Science Foundation. L-W.T. was supported by a fellowship from the University of Minnesota Plant Molecular Genetics Institute, and by a National Research Service Award from the NIAID (F32 AI08942).

PY - 1995

Y1 - 1995

N2 - The flagella of the unicellular green alga Chlamydomonas reinhardtii are controlled by a number of sophisticated homeostatic mechanisms which ensure that the flagella are maintained at a specific length, and that each cell has two flagella of equal length. Mutants with defects in flagellar length control have been obtained, defining at least nine genes that are involved in the control of flagellar length and the equality of flagellar length. The active machinery involved in flagellar length control requires that cells precisely measure the length of their flagella and drastically alter flagellar protein production and assembly when necessary to maintain desired lengths.

AB - The flagella of the unicellular green alga Chlamydomonas reinhardtii are controlled by a number of sophisticated homeostatic mechanisms which ensure that the flagella are maintained at a specific length, and that each cell has two flagella of equal length. Mutants with defects in flagellar length control have been obtained, defining at least nine genes that are involved in the control of flagellar length and the equality of flagellar length. The active machinery involved in flagellar length control requires that cells precisely measure the length of their flagella and drastically alter flagellar protein production and assembly when necessary to maintain desired lengths.

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JF - Seminars in Developmental Biology

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ER -

Control of flagellar length in Chlamydomonas

Abstract

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Keywords

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