Abstract
With the help of single molecule force spectroscopy and molecular dynamics simulations, we determine the surface-induced structure of a single engineered spider silk protein. An amyloid like structure is induced in the vicinity of a surface with high surface energy and can be prohibited in the presence of a hydrophobic surface. The derived molecular energy landscapes highlight the role of single silk protein structure for the macroscopic toughness of spider silk.
Original language | English (US) |
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Pages (from-to) | 17277-17281 |
Number of pages | 5 |
Journal | Journal of the American Chemical Society |
Volume | 132 |
Issue number | 48 |
DOIs | |
State | Published - Dec 8 2010 |