Abstract
Prior examples of hydroacylation to form six- and seven-membered ring ketones require either embedded chelating groups or other substrate design strategies to circumvent competitive aldehyde decarbonylation. A cooperative catalysis strategy enabled intramolecular hydroacylation of disubstituted alkenes to form seven- and six-membered rings without requiring substrate-embedded chelating groups.
Original language | English (US) |
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Pages (from-to) | 5884-5893 |
Number of pages | 10 |
Journal | Journal of Organic Chemistry |
Volume | 77 |
Issue number | 14 |
DOIs | |
State | Published - Jul 20 2012 |