Coordination microparticle vaccines engineered from tumor cell templates

Xiaoli Wang, Jiayi Liang, Chuangnian Zhang, Guilei Ma, Chun Wang, Deling Kong

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

A method for encapsulation of individual tumor cells with an epigallocatechin-3-gallate (EGCG)-Al(iii) coordination layer, which can be used as potential tumor vaccines, was developed. The interaction between microparticle vaccines and dendritic cells was investigated in vitro. The microparticles (∼10 μm) were efficiently internalized by DCs with enhanced uptake efficiency via actin polymerization and clathrin-mediated endocytosis.

Original languageEnglish (US)
Pages (from-to)1568-1571
Number of pages4
JournalChemical Communications
Volume55
Issue number11
DOIs
StatePublished - Jan 1 2019

PubMed: MeSH publication types

  • Journal Article

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