Crohn's disease-Associated interstitial lung disease mimicking sarcoidosis: A case report and review of the literature

Choua Thao, A. Amir Lagstein, Tadashi L Allen, H. Erhan Dincer, Hyun J Kim

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Respiratory involvement in Crohn's disease (CD) is a rare manifestation known to involve the large and small airways, lung parenchyma, and pleura. The clinical presentation is nonspecific, and diagnostic tests can mimic other pulmonary diseases, posing a diagnostic challenge and delay in treatment. We report a case of a 60-year-old female with a history of CD and psoriatic arthritis who presented with dyspnea, fever, and cough with abnormal radiological findings. Diagnostic testing revealed an elevated CD4:CD8 ratio in the bronchoalveolar lavage fluid, and cryoprobe lung biopsy results showed non-necrotizing granulomatous inflammation. We describe here the second reported case of pulmonary involvement mimicking sarcoidosis in Crohn's disease and a review of the literature on the approaches to making a diagnosis of CD-Associated interstitial lung disease.

Original languageEnglish (US)
Pages (from-to)288-291
Number of pages4
JournalSarcoidosis Vasculitis and Diffuse Lung Diseases
Volume33
Issue number3
StatePublished - Jan 1 2016

Keywords

  • Crohns disease
  • Cryoprobe lung biopsy
  • Interstitial lung disease
  • Sarcoidosis

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