Cyclosporine and Immunosuppressive Regimens in Renal Transplantation

D. M. Canafax, D. E R Sutherland, A. J. Matas, W. D. Payne, D. L. Dunn, J. S. Najarian, B. M. Hall

Research output: Contribution to journalLetterpeer-review

2 Scopus citations


To the Editor: Hall et al. have recently reported on a trial of immunosuppressive drugs in renal transplantation that compares a short-term cyclosporine protocol (three months of cyclosporine followed by conversion to prednisolone and azathioprine) with the traditional long-term cyclosporine and azathioprine–prednisolone protocols.1 They observed equivalent allograft survival rates in all groups, but the patients who were given short-term cyclosporine had significantly lower serum creatinine levels than those in the long-term cyclosporine group. We have a number of concerns about the interpretation of these data and their application to current practice. Some patients in each of the treatment groups had.

Original languageEnglish (US)
Pages (from-to)1287-1288
Number of pages2
JournalNew England Journal of Medicine
Issue number19
StatePublished - Nov 10 1988

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