[D-Thr2, Thz5]-enkephalinamide: A potent analgesic by subcutaneous and oral administration

Liang Fu Tseng, Horace H. Loh, Choh Hao Li

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


[D-Thr2, Thz5]-enkephalinamide administered orally or subcutaneously inhibited the tail-flick response to heat stimuli in mice. On a molar basis, this peptide was found to be 1.5-1.7 times more potent than morphine by oral administration.

Original languageEnglish (US)
Pages (from-to)2053-2056
Number of pages4
JournalLife Sciences
Issue number20
StatePublished - Nov 13 1978

Bibliographical note

Funding Information:
This work was supported in part by grants from NIDA No . DA-01314 (to L-F . T,), DA-00564 (to H .H .L .), NIMH MH-30245 and Hormone Research Foundation (to C .H .L .) .


Dive into the research topics of '[D-Thr<sup>2</sup>, Thz<sup>5</sup>]-enkephalinamide: A potent analgesic by subcutaneous and oral administration'. Together they form a unique fingerprint.

Cite this