TY - JOUR
T1 - Declining invasive pneumococcal disease in the U.S. elderly
AU - McBean, Alexander M
AU - Park, Young Taek
AU - Caldwell, Debra
AU - Yu, Xinhua
N1 - Copyright:
Copyright 2008 Elsevier B.V., All rights reserved.
PY - 2005/12/1
Y1 - 2005/12/1
N2 - In 2000, pneumococcal conjugate vaccine (PCV7) was recommended for young children. By 2002-2003, 48.6% had been fully immunized. Using Medicare administrative, we found that the rates of invasive pneumococcal disease (IPD) hospitalizations in the elderly in the 2000-2001, 2001-2002 and 2002-2003, were 22.6, 30.2, and 40.6% lower, respectively, than during the baseline period, 1996-1997 through 1999-2000 (range 35.1/100,000 to 38.3/100,000). Pneumococcal polysaccharide vaccine (PPV23) has been recommended for the elderly, since 1989. PPV23 vaccination rates in the elderly increased by 25.2% during the baseline period but by <5% during the period PCV7 has been available. Thus, during the period that PCV7 vaccine has been used in children, rates of IPD in the elderly have declined appreciably more compared to the immediately prior period when PPV23 was the only vaccine available.
AB - In 2000, pneumococcal conjugate vaccine (PCV7) was recommended for young children. By 2002-2003, 48.6% had been fully immunized. Using Medicare administrative, we found that the rates of invasive pneumococcal disease (IPD) hospitalizations in the elderly in the 2000-2001, 2001-2002 and 2002-2003, were 22.6, 30.2, and 40.6% lower, respectively, than during the baseline period, 1996-1997 through 1999-2000 (range 35.1/100,000 to 38.3/100,000). Pneumococcal polysaccharide vaccine (PPV23) has been recommended for the elderly, since 1989. PPV23 vaccination rates in the elderly increased by 25.2% during the baseline period but by <5% during the period PCV7 has been available. Thus, during the period that PCV7 vaccine has been used in children, rates of IPD in the elderly have declined appreciably more compared to the immediately prior period when PPV23 was the only vaccine available.
KW - Elderly
KW - Invasive pneumococcal disease
KW - Pneumococcal conjugate vaccine
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U2 - 10.1016/j.vaccine.2005.05.043
DO - 10.1016/j.vaccine.2005.05.043
M3 - Article
C2 - 16111788
AN - SCOPUS:27744455512
SN - 0264-410X
VL - 23
SP - 5641
EP - 5645
JO - Vaccine
JF - Vaccine
IS - 48-49
ER -