Decreased affinity for efflux transporters increases brain penetrance and molecular targeting of a PI3K/mTOR inhibitor in a mouse model of glioblastoma

Chani M. Becker, Rajneet K. Oberoi, Stephan J. McFarren, Daniel M. Muldoon, Deanna H. Pafundi, Jenny L. Pokorny, Debra H. Brinkmann, John R. Ohlfest, Jann N. Sarkaria, David A. Largaespada, William F. Elmquist

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