TY - JOUR
T1 - Design of self-assembling protein-polymer conjugates
AU - Carter, Nathan A
AU - Geng, Xi
AU - Grove, Tijana Z.
PY - 2016/9/1
Y1 - 2016/9/1
N2 - Protein-polymer conjugates are of particular interest for nanobiotechnology applications because of the various and complementary roles that each component may play in composite hybrid-materials. This chapter focuses on the design principles and applications of self-assembling protein- polymer conjugate materials. We address the general design methodology, from both synthetic and genetic perspective, conjugation strategies, protein vs. polymer driven self-assembly and finally, emerging applications for conjugate materials. By marrying proteins and polymers into conjugated bio-hybrid materials, materials scientists, chemists, and biologists alike, have at their fingertips a vast toolkit for material design. These inherently hierarchical structures give rise to useful patterning, mechanical and transport properties that may help realize new, more efficient materials for energy generation, catalysis, nanorobots, etc.
AB - Protein-polymer conjugates are of particular interest for nanobiotechnology applications because of the various and complementary roles that each component may play in composite hybrid-materials. This chapter focuses on the design principles and applications of self-assembling protein- polymer conjugate materials. We address the general design methodology, from both synthetic and genetic perspective, conjugation strategies, protein vs. polymer driven self-assembly and finally, emerging applications for conjugate materials. By marrying proteins and polymers into conjugated bio-hybrid materials, materials scientists, chemists, and biologists alike, have at their fingertips a vast toolkit for material design. These inherently hierarchical structures give rise to useful patterning, mechanical and transport properties that may help realize new, more efficient materials for energy generation, catalysis, nanorobots, etc.
KW - Bio-hybrid materials
KW - Conjugation strategies
KW - Molecular-scale interactions
KW - Nanostructural design
KW - Proteinpolymer conjugates
KW - Self-assembly
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U2 - 10.1007/978-3-319-39196-0_9
DO - 10.1007/978-3-319-39196-0_9
M3 - Article
C2 - 27677514
AN - SCOPUS:84988920904
SN - 0065-2598
VL - 940
SP - 179
EP - 214
JO - Advances in Experimental Medicine and Biology
JF - Advances in Experimental Medicine and Biology
ER -