Two new diprenylquinones, glabruquinone A (desmethylubiquinone Q 2) having cancer preventive properties and its minor isomer Glabruquinone B were isolated from the ascidian Aplidium glabrum. Their structures have been elucidated by NMR and mass spectra and confirmed by synthesis.
Bibliographical noteFunding Information:
We are grateful to B. B. Grebnev for identification of the ascidian. The research described in this publication was made possible in part by Grant NS-725.2003.4 of RFBR and a Grant from the Program ‘Molecular and cell biology of RAS’.
- Cancer preventive activity
- Marine natural products
- Polyprenylated quinones