TY - JOUR
T1 - Detection of antiretroviral resistance in HIV-1
AU - Cavert, Winston
AU - Balfour, Henry H.
PY - 2003/12
Y1 - 2003/12
N2 - Resistance testing should be readily available to every clinician who specializes in HIV/AIDS. Based in part on requests we receive in our laboratory, we believe that the use of resistance testing is expanding. However, selecting an initial antiretroviral treatment regimen or changing a failing one according to the test results is complex and inexact and requires knowledgeable interpretation to maximize the clinical benefit. Future studies about viral fitness and other viral, host, and pharmacologic factors responsible for disease progression likely will facilitate more precise application of resistance testing to the clinical setting.
AB - Resistance testing should be readily available to every clinician who specializes in HIV/AIDS. Based in part on requests we receive in our laboratory, we believe that the use of resistance testing is expanding. However, selecting an initial antiretroviral treatment regimen or changing a failing one according to the test results is complex and inexact and requires knowledgeable interpretation to maximize the clinical benefit. Future studies about viral fitness and other viral, host, and pharmacologic factors responsible for disease progression likely will facilitate more precise application of resistance testing to the clinical setting.
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U2 - 10.1016/S0272-2712(03)00083-0
DO - 10.1016/S0272-2712(03)00083-0
M3 - Review article
C2 - 14711099
AN - SCOPUS:0346881429
SN - 0272-2712
VL - 23
SP - 915
EP - 928
JO - Clinics in Laboratory Medicine
JF - Clinics in Laboratory Medicine
IS - 4
ER -
