Development of Candida albicans and C. albicans/Escherichia coli/Bacteroides fragilis intraperitoneal abscess models with demonstration of fungus-induced bacterial translocation

R. G. Sawyer, R. B. Adams, A. K. May, L. K. Rosenlof, T. L. Pruett

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

The development of models of both Candida albicans and mixed C. albicans/Escherichia coli/Bacillus fragilis peritonitis in immunologically normal mice are described, each with significant mortality and intra-abdominal abscess formation. C. albicans inoculated alone induced bacterial translocation into abscesses, and the addition of bacteria reduced the number of, but did not eliminate, C. albicans in abscesses. There was no synergy seen between fungi and bacteria in terms of either morbidity or mortality.

Original languageEnglish (US)
Pages (from-to)49-52
Number of pages4
JournalMedical Mycology
Volume33
Issue number1
DOIs
StatePublished - 1995

Fingerprint

Dive into the research topics of 'Development of Candida albicans and C. albicans/Escherichia coli/Bacteroides fragilis intraperitoneal abscess models with demonstration of fungus-induced bacterial translocation'. Together they form a unique fingerprint.

Cite this