Developmental changes in hepatic IGF-2 and IGFBP-2 mRNA levels in intrauterine growth-retarded and control swine

Kimberly A. Kampman; Timothy G. Ramsay; Michael E. White

doi:10.1016/0305-0491(93)90388-L

Developmental changes in hepatic IGF-2 and IGFBP-2 mRNA levels in intrauterine growth-retarded and control swine

Kimberly A. Kampman, Timothy G. Ramsay, Michael E. White

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11 Scopus citations

Abstract

1. 1. Significantly elevated levels of hepatic IGFBP-2 mRNA were detected in IUGR piglets at 90 days fetally and at birth (P < 0.05). 2. 2. Developmentally, hepatic IGF-2 (P < 0.05) and IGFBP-2 (P < 0.01) mRNA levels were higher fetally and at birth than at 21 and 49 days of age. 3. 3. This study provides new information concerning hepatic expression of IGF-2 and IGFBP-2 in developing swine.

Original language	English (US)
Pages (from-to)	415-421
Number of pages	7
Journal	Comparative Biochemistry and Physiology -- Part B: Biochemistry and
Volume	104
Issue number	2
DOIs	https://doi.org/10.1016/0305-0491(93)90388-L
State	Published - Feb 1993

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title = "Developmental changes in hepatic IGF-2 and IGFBP-2 mRNA levels in intrauterine growth-retarded and control swine",

abstract = "1. 1. Significantly elevated levels of hepatic IGFBP-2 mRNA were detected in IUGR piglets at 90 days fetally and at birth (P < 0.05). 2. 2. Developmentally, hepatic IGF-2 (P < 0.05) and IGFBP-2 (P < 0.01) mRNA levels were higher fetally and at birth than at 21 and 49 days of age. 3. 3. This study provides new information concerning hepatic expression of IGF-2 and IGFBP-2 in developing swine.",

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AU - Kampman, Kimberly A.

AU - Ramsay, Timothy G.

AU - White, Michael E.

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Y1 - 1993/2

N2 - 1. 1. Significantly elevated levels of hepatic IGFBP-2 mRNA were detected in IUGR piglets at 90 days fetally and at birth (P < 0.05). 2. 2. Developmentally, hepatic IGF-2 (P < 0.05) and IGFBP-2 (P < 0.01) mRNA levels were higher fetally and at birth than at 21 and 49 days of age. 3. 3. This study provides new information concerning hepatic expression of IGF-2 and IGFBP-2 in developing swine.

AB - 1. 1. Significantly elevated levels of hepatic IGFBP-2 mRNA were detected in IUGR piglets at 90 days fetally and at birth (P < 0.05). 2. 2. Developmentally, hepatic IGF-2 (P < 0.05) and IGFBP-2 (P < 0.01) mRNA levels were higher fetally and at birth than at 21 and 49 days of age. 3. 3. This study provides new information concerning hepatic expression of IGF-2 and IGFBP-2 in developing swine.

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Developmental changes in hepatic IGF-2 and IGFBP-2 mRNA levels in intrauterine growth-retarded and control swine

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