TY - JOUR
T1 - Diabetic ketoacidosis and hyperosmolar nonketotic state
T2 - Gaining control over extreme hyperglycemic complications
AU - Michael Gonzalez-Campoy, J.
AU - Robertson, R. Paul
PY - 1996
Y1 - 1996
N2 - Decompensated hyperglycemia is a frequent, severe complication of diabetes mellitus. Ketoacidosis usually occurs in patients with insulin-dependent (type I) diabetes, and insulin therapy is required to correct their hyperglycemic derangement. Hyperosmolar nonketotic state is more common in patients with non-insulin- dependent (type II) diabetes, who usually present with severe dehydration and hyperosmolar plasma. They respond readily to aggressive volume expansion, and insulin has a lesser role in management. Some patients exhibit a mix ture of ketoacidosis and hyperosmolarity, which suggests that the two conditions may represent variants of decompensated by the magnitude of dehydration and the severity of acidosis. All diabetic patients with hyperglycemic decompensation should return to their usual hypoglycemic programs as soon as possible and receive close follow-up after hospitalization.
AB - Decompensated hyperglycemia is a frequent, severe complication of diabetes mellitus. Ketoacidosis usually occurs in patients with insulin-dependent (type I) diabetes, and insulin therapy is required to correct their hyperglycemic derangement. Hyperosmolar nonketotic state is more common in patients with non-insulin- dependent (type II) diabetes, who usually present with severe dehydration and hyperosmolar plasma. They respond readily to aggressive volume expansion, and insulin has a lesser role in management. Some patients exhibit a mix ture of ketoacidosis and hyperosmolarity, which suggests that the two conditions may represent variants of decompensated by the magnitude of dehydration and the severity of acidosis. All diabetic patients with hyperglycemic decompensation should return to their usual hypoglycemic programs as soon as possible and receive close follow-up after hospitalization.
UR - http://www.scopus.com/inward/record.url?scp=3043002680&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=3043002680&partnerID=8YFLogxK
U2 - 10.1080/00325481.1996.11946141
DO - 10.1080/00325481.1996.11946141
M3 - Article
C2 - 8668627
AN - SCOPUS:0030000028
SN - 0032-5481
VL - 99
SP - 143
EP - 152
JO - Postgraduate Medicine
JF - Postgraduate Medicine
IS - 6
ER -