This report describes preliminary work on the use of signal processing of backscattered ultrasound data for characterizing tissue regions undergoing thermal therapy. The long term objective is to test the hypothesis that pulse-echo ultrasound data from treated tissue, with appropriate signal processing, can provide useful parameters for assessment of tissue state during and after undergoing thermal coagulative therapy. One very promising tissue parameter is tissue attenuation which is known to change drastically in tissues subject to coagulative necrosis. This report presents experimental in-vitro data that strongly support the above hypothesis. Statistical methods for characterization of reversible and irreversible changes in tissue state appear to hold the most promise for providing a solution to this problem.
|Original language||English (US)|
|Number of pages||6|
|Journal||Proceedings of SPIE - The International Society for Optical Engineering|
|State||Published - Jan 1 1999|