Dipole-tracing method applied to human brain potentials

Saburo Homma, Yoshio Nakajima, Toshimitsu Musha, Yoshio Okamoto, Bin He

Research output: Contribution to journalArticlepeer-review

43 Scopus citations

Abstract

A new computer-aided method was developed to estimate the location of an electric source generator (e.g. a current dipole) in the human brain. Brain activity such as somatosensory evoked potentials was recorded with 21 surface electrodes over the scalp. To solve the inverse problem, it was assumed that only one dipole is elicited at a given time, and that the head is embedded in an infinite and homogeneous conductor. The exact geometry of the human head was measured from 17 slices of CT-images of a real head to arrange a human head model. A dipole with a given moment and location is assumed in the head model. Potential distribution elicited by the dipole is compared with potential distribution which was the actual recorded one. The optimal dipole location was calculated, using the simplex method. Hence, the optimal dipole moment was obtained. The accuracy of estimation as an equivalent dipole was expressed in terms of dipolarity.

Original languageEnglish (US)
Pages (from-to)195-200
Number of pages6
JournalJournal of Neuroscience Methods
Volume21
Issue number2-4
DOIs
StatePublished - Oct 1987

Keywords

  • Current dipole
  • Infinite conductor model
  • Inverse problem
  • Somatosensory evoked potential

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