Direct correlation among crystal structure, mechanical behaviour and tabletability in a trimorphic molecular compound

Partha Pratim Bag, Miles Chen, Changquan Calvin Sun, C. Malla Reddy

Research output: Contribution to journalArticlepeer-review


Powder compaction data of three polymorphic Forms I (shearing), II (bending) and III (brittle) of 6-chloro-2,4-dinitroaniline demonstrates a direct relationship among mechanical properties, crystal structure and tableting behaviour, showing the essence of structure based assessment of mechanical properties of crystals, e.g., for identifying more efficient API formulation and manufacture processes.

Original languageEnglish (US)
Pages (from-to)3865-3867
Number of pages3
Issue number11
StatePublished - Jun 7 2012

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