Abstract
Clinical isolates of Streptococcus faecalis were examined for plasmid content and plasmid-related traits in order to determine whether such strains carried conjugative antibiotic resistance plasmids whose transfer was stimulated by sex pheromones. A 35-Mdalton tetracycline-resistance plasmid called pCF-10 was identified. pCF-10 carries genes that enable its host cell to clump and to act as a highly effective donor when exposed to sex pheromone preparations from recipients. The genetic background of the host cell markedly affects the expression of the pCF-10 fertility functions. The properties of this plasmid make it a good candidate for a detailed genetic analysis of streptococcal conjugation.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 270-278 |
| Number of pages | 9 |
| Journal | Plasmid |
| Volume | 6 |
| Issue number | 3 |
| DOIs | |
| State | Published - Nov 1981 |