A direct, Grignard reagent-based route for the syntheses of [2-(CF3)C6H4]2P(O)H(1) and [3,5-(CF3)2C6H3]2P(O)H (2) has been developed and the isolation and characterization of these crystalline reagents is described. The crystal structures for 1 and 2 were determined and the structure of 1 reveals unexpected close non-bonded interaction between F-atoms of one CF3 group and the back-side of the central phosphorus atom.
- Grignard reagent
- Non-bonded phosphorus-fluorine interactions
- Trifluoromethyl group
- X-ray crystal structures