TY - JOUR
T1 - Discriminative value of lipids and apolipoproteins in alcoholics
AU - Vaswani, M.
AU - Hemraj, P.
AU - Rajbir, S.
PY - 2001
Y1 - 2001
N2 - 1. It is important to detect alcohol use in its early stages so that interventions can be planned effectively. In a bid to screen for alcohol use disorders various biochemical assessments have been advocated. 2. It has been seen that moderate to heavy alcohol consumption appears to elevate ApoA1 though the effect of alcohol consumption on ApoB is not well defined. 3. Present study was planned to evaluate the contribution of lipid profile and lipoprotein measures for the diagnosis of alcohol use disorder in 75 alcohol dependent and 45 normal healthy controls. 4. Based on the TC,TG, HDL/LDL-c, HDL-c/TC, ApoA1, ApoB, and ApoA1/ApoB a discriminant equation was developed for classification of alcohol dependent users (alcoholics) and non-users (non-alcoholics) 5. The discriminant equation resulted in 84.7% of subjects being correctly classified. (94.7% in non-users and 81.1% in alcohol dependent users as alcoholics).
AB - 1. It is important to detect alcohol use in its early stages so that interventions can be planned effectively. In a bid to screen for alcohol use disorders various biochemical assessments have been advocated. 2. It has been seen that moderate to heavy alcohol consumption appears to elevate ApoA1 though the effect of alcohol consumption on ApoB is not well defined. 3. Present study was planned to evaluate the contribution of lipid profile and lipoprotein measures for the diagnosis of alcohol use disorder in 75 alcohol dependent and 45 normal healthy controls. 4. Based on the TC,TG, HDL/LDL-c, HDL-c/TC, ApoA1, ApoB, and ApoA1/ApoB a discriminant equation was developed for classification of alcohol dependent users (alcoholics) and non-users (non-alcoholics) 5. The discriminant equation resulted in 84.7% of subjects being correctly classified. (94.7% in non-users and 81.1% in alcohol dependent users as alcoholics).
KW - Alcoholism
KW - Discriminant analysis
KW - Lipids
UR - http://www.scopus.com/inward/record.url?scp=0034882960&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0034882960&partnerID=8YFLogxK
U2 - 10.1016/S0278-5846(01)00176-2
DO - 10.1016/S0278-5846(01)00176-2
M3 - Article
C2 - 11444674
AN - SCOPUS:0034882960
SN - 0278-5846
VL - 25
SP - 1011
EP - 1022
JO - Progress in Neuro-Psychopharmacology and Biological Psychiatry
JF - Progress in Neuro-Psychopharmacology and Biological Psychiatry
IS - 5
ER -
