There are many nonpharmacologic interventions tested in randomized clinical trials that demonstrate significant benefits for people living with Alzheimer's disease (AD) and AD-related dementia, their care partners, or professional care providers. Nevertheless, with few exceptions, proven interventions have not been translated for delivery in real-world settings, such as home care, primary care, hospitals, community-based services, adult day services, assisted living, nursing homes, or other healthcare systems (HCSs). Using embedded pragmatic clinical trial (ePCT) methods is one approach that can facilitate dissemination and implementation (D&I) of dementia care interventions. The science of D&I can inform the integration of evidence-based dementia care in HCSs by offering theoretical frameworks that capture field complexities and guiding evaluation of implementation processes. Also, D&I science can suggest evidence-based strategies for implementing dementia care in HCSs. Although D&I considerations can inform each stage of dementia care intervention development, it is particularly critical when designing ePCTs. This article examines fundamental considerations for implementing dementia-specific interventions in HCSs and how best to prepare for successful dissemination upstream in the context of ePCTs, thereby illustrating the critical role of the D&I Core of the National Institute on Aging Imbedded Pragmatic Alzheimer's Disease and AD-Related Dementias Clinical Trials Collaboratory. The scientific premise of the D&I Core is that having the “end” in mind, upfront in the design and testing of dementia care programs, can lead to decision-making that optimizes the ultimate goal of wide-scale D&I of evidence-based dementia care programs in HCSs. J Am Geriatr Soc 68:S28–S36, 2020.
Bibliographical noteFunding Information:
In addition to the listed authors, who are members of the Dissemination and Implementation (D&I) Core, we wish to acknowledge D&I members who critically reviewed the manuscript: John Beilenson, Marie Boltz, PhD, RN, Richard Fortinsky, PhD, and Kimberly S. Van Haitsma, PhD. This work was supported by the National Institute on Aging (NIA) of the National Institutes of Health under Award U54AG063546, which funds the NIA Imbedded Pragmatic Alzheimer's Disease (AD) and AD-Related Dementias Clinical Trials Collaboratory. All authors participated in writing, reviewing, and editing. Dissemination and Implementation Core members who are acknowledged read the manuscript critically. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.
Dissemination and implementation research funded by the US National Institutes of Health, 2005‐2012
- dementia care
- healthcare systems