Distinguishing the viability of a single yeast cell with an ultra-sensitive radio frequency sensor

Yang Yang, Hanqiao Zhang, Junjie Zhu, Gaoyan Wang, Tzuen Rong Tzeng, Xiangchun Xuan, Kama Huang, Pingshan Wang

Research output: Contribution to journalArticlepeer-review

76 Scopus citations

Abstract

We propose and demonstrate a simple, ultra sensitive radio frequency (RF) sensor to detect a single yeast cell and distinguish its viability in a microfluidic channel. On-chip interference is used to cancel background probing signals to improve sensor sensitivity. Individual viable and nonviable yeast cells (∼ 5.83 ± 0.85 μm in diameter) are measured with clear sensing and identification of these cells.

Original languageEnglish (US)
Pages (from-to)553-555
Number of pages3
JournalLab on a chip
Volume10
Issue number5
DOIs
StatePublished - 2010

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