Distribution of phosphofructokinase isozymes in rabbit, mouse, guinea pig and rat

Fresia González, Michael Y. Tsai, Robert G. Kemp

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18 Scopus citations

Abstract

1. 1. The distribution of phosphofructokinase total activity and isozyme patterns have been compared among rabbit, rat, guinea pig, and mouse tissues. 2. 2. In all species, the patterns were basically similar with PFK-A present as the sole or major form of muscle and heart and with PFK-B the major or sole form of liver and erythrocytes. 3. 3. Electrophoretic patterns indicated the presence of hybrid isozymes in all species. 4. 4. Antisera prepared against purified rabbit muscle and liver phosphofructokinases were capable of binding phosphofructokinases of rat and mouse.

Original languageEnglish (US)
Pages (from-to)315-319
Number of pages5
JournalComparative Biochemistry and Physiology -- Part B: Biochemistry and
Volume52
Issue number2
DOIs
StatePublished - Oct 15 1975
Externally publishedYes

Bibliographical note

Funding Information:
Acknowledgements--The authors are indebted to Miss Alice Hsu for excellent technical assistance. This work was supported by U.S. Public Health Service grant AM 11410 and by American Cancer Society grant BC 114.

Keywords

  • Rabbit
  • guinea pig
  • isozymes
  • mouse
  • phosphofructokinase
  • rat

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