Diverse CD8 T Cell Responses to Viral Infection Revealed by the Collaborative Cross

Matthew D. Martin; Ramakrishna Sompallae; Christina S. Winborn; John T. Harty; Vladimir P. Badovinac

doi:10.1016/j.celrep.2020.03.072

Diverse CD8 T Cell Responses to Viral Infection Revealed by the Collaborative Cross

Matthew D. Martin, Ramakrishna Sompallae, Christina S. Winborn, John T. Harty, Vladimir P. Badovinac

Urology

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

Martin et al. advance the use of the Collaborative Cross (CC) for studying adaptive immune responses. They demonstrate that the CC better models variation in T cell responses seen in outbred mice and humans and that it can uncover genes linked to generation of qualitatively distinct memory cells following infection.

Original language	English (US)
Article number	107508
Journal	Cell reports
Volume	31
Issue number	2
DOIs	https://doi.org/10.1016/j.celrep.2020.03.072
State	Published - Apr 14 2020

Bibliographical note

Publisher Copyright:
© 2020 The Author(s)

Keywords

CD8 T cells
QTL mapping
central memory
collaborative cross
immunological memory
mouse models

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10.1016/j.celrep.2020.03.072

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Diverse CD8 T Cell Responses to Viral Infection Revealed by the Collaborative Cross

Abstract

Bibliographical note

Keywords

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