TY - JOUR
T1 - Do donor characteristics really matter? Short- and long-term impact of donor characteristics on recipient survival, 1995-1999
AU - Chen, Jonathan M.
AU - Sinha, Prashant
AU - Rajasinghe, Hiranya A.
AU - Suratwala, Sanjeev J.
AU - McCue, Jonathan D.
AU - McCarty, Matthew J.
AU - Caliste, Xzabia
AU - Hauff, Helen M.
AU - John, Ranjit
AU - Edwards, Niloo M.
PY - 2002
Y1 - 2002
N2 - We reviewed the impact of multiple donor characteristics on recipient mortality by univariate and multivariate analyses in a cohort of heart donors from 1995 to 1999. A sub-cohort of donors was also selected who met "marginal" criteria, and the early and late survival of these patients was then compared. Surrogates of donor size (donor weight, donor body mass index [BMI], BMI mismatch >20%), under-resuscitation (hematocrit, 24-hour fluid intake) and age >56 years were significantly associated with peri-operative mortality in the univariate analysis; in the multivariate analysis, only average donor heart rate at procurement (p = .001), donor hematocrit (p = .02) and donor weight (p = .05) were significantly associated. Few donor characteristics actually impact significantly on recipient outcome, and thus recipient characteristics may figure more prominently than those of the donor toward the risk of death after transplantation.
AB - We reviewed the impact of multiple donor characteristics on recipient mortality by univariate and multivariate analyses in a cohort of heart donors from 1995 to 1999. A sub-cohort of donors was also selected who met "marginal" criteria, and the early and late survival of these patients was then compared. Surrogates of donor size (donor weight, donor body mass index [BMI], BMI mismatch >20%), under-resuscitation (hematocrit, 24-hour fluid intake) and age >56 years were significantly associated with peri-operative mortality in the univariate analysis; in the multivariate analysis, only average donor heart rate at procurement (p = .001), donor hematocrit (p = .02) and donor weight (p = .05) were significantly associated. Few donor characteristics actually impact significantly on recipient outcome, and thus recipient characteristics may figure more prominently than those of the donor toward the risk of death after transplantation.
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U2 - 10.1016/S1053-2498(01)00367-9
DO - 10.1016/S1053-2498(01)00367-9
M3 - Article
C2 - 11983553
AN - SCOPUS:0036253018
SN - 1053-2498
VL - 21
SP - 608
EP - 610
JO - Journal of Heart and Lung Transplantation
JF - Journal of Heart and Lung Transplantation
IS - 5
ER -