Dopaminergic modulation of striatal networks in health and Parkinson's disease

D. James Surmeier; Steven M. Graves; Weixing Shen

doi:10.1016/j.conb.2014.07.008

Dopaminergic modulation of striatal networks in health and Parkinson's disease

D. James Surmeier, Steven M. Graves, Weixing Shen

Research output: Contribution to journal › Review article › peer-review

104 Scopus citations

Abstract

In the last couple of years, there have been significant advances in our understanding of how dopamine modulates striatal circuits underlying goal-directed behaviors and how therapeutic interventions intended to normalize disordered dopaminergic signaling can go awry. This review summarizes some of the advances in this field with a translational focus on Parkinson's disease.

Original language	English (US)
Pages (from-to)	109-117
Number of pages	9
Journal	Current opinion in neurobiology
Volume	29
DOIs	https://doi.org/10.1016/j.conb.2014.07.008
State	Published - Dec 2014
Externally published	Yes

Bibliographical note

Funding Information:
This work was supported by grants from NIH ( NS 34696 and NS 084735 ) and from the IDP and JPB Foundations.

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title = "Dopaminergic modulation of striatal networks in health and Parkinson's disease",

abstract = "In the last couple of years, there have been significant advances in our understanding of how dopamine modulates striatal circuits underlying goal-directed behaviors and how therapeutic interventions intended to normalize disordered dopaminergic signaling can go awry. This review summarizes some of the advances in this field with a translational focus on Parkinson's disease.",

author = "Surmeier, {D. James} and Graves, {Steven M.} and Weixing Shen",

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AU - Graves, Steven M.

AU - Shen, Weixing

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AB - In the last couple of years, there have been significant advances in our understanding of how dopamine modulates striatal circuits underlying goal-directed behaviors and how therapeutic interventions intended to normalize disordered dopaminergic signaling can go awry. This review summarizes some of the advances in this field with a translational focus on Parkinson's disease.

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Dopaminergic modulation of striatal networks in health and Parkinson's disease

Abstract

Bibliographical note

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