TY - JOUR
T1 - Drawing in poly(ϵ-caprolactone) fibers
T2 - Tuning mechanics, fiber dimensions and surface-modification density
AU - Kim, Si Eun
AU - Jordan, Alex M.
AU - Korley, Lashanda T.J.
AU - Pokorski, Jonathan K.
N1 - Publisher Copyright:
© 2017 The Royal Society of Chemistry.
PY - 2017
Y1 - 2017
N2 - Uniaxial drawing of melt-coextruded poly(ϵ-caprolactone) (PCL) microfibers was investigated to understand impact on topological, mechanical, and chemical properties of the fibrous scaffolds. Fibers were uniaxially elongated up to 7-fold to observe polymer chain orientation and crystal structure. Crystallinity and orientation of crystal domains were investigated by DSC and X-ray scattering. Polymer physical properties were directly correlated to bulk fiber properties. Furthermore, the drawn fibers were modified photochemically with functionalized benzophenones. The results of these studies allowed for comparison between fiber dimension/surface area, mechanical properties, and photochemical reaction yield for surface modification. As drawing increased, the modulus and tensile strength of the fibers increased as did the surface area of the scaffolds. By contrast, increased drawing led to a decrease in the ability to undergo photochemical reaction at the polymer surface. This fundamental investigation provides a predictive framework to understand how post-processing impacts three critical parameters for coextruded fibrous biomaterial scaffolds.
AB - Uniaxial drawing of melt-coextruded poly(ϵ-caprolactone) (PCL) microfibers was investigated to understand impact on topological, mechanical, and chemical properties of the fibrous scaffolds. Fibers were uniaxially elongated up to 7-fold to observe polymer chain orientation and crystal structure. Crystallinity and orientation of crystal domains were investigated by DSC and X-ray scattering. Polymer physical properties were directly correlated to bulk fiber properties. Furthermore, the drawn fibers were modified photochemically with functionalized benzophenones. The results of these studies allowed for comparison between fiber dimension/surface area, mechanical properties, and photochemical reaction yield for surface modification. As drawing increased, the modulus and tensile strength of the fibers increased as did the surface area of the scaffolds. By contrast, increased drawing led to a decrease in the ability to undergo photochemical reaction at the polymer surface. This fundamental investigation provides a predictive framework to understand how post-processing impacts three critical parameters for coextruded fibrous biomaterial scaffolds.
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U2 - 10.1039/c7tb00096k
DO - 10.1039/c7tb00096k
M3 - Review article
AN - SCOPUS:85021672783
SN - 2050-7518
VL - 5
SP - 4499
EP - 4506
JO - Journal of Materials Chemistry B
JF - Journal of Materials Chemistry B
IS - 23
ER -