TY - JOUR
T1 - Drugs in use in the newborn
T2 - Effects on the kidney
AU - Wahlig, T. M.
AU - Thompson, T. R.
AU - Sinaiko, Alan R
PY - 1992
Y1 - 1992
N2 - In the neonate, there are a number of age-related differences in drug disposition (bioavailability, distribution, metabolism, and excretion), and these are directly related to the degree of prematurity. This article discusses the use of drugs that are commonly administered to the neonatal patient, with special emphasis given to renal considerations. These drugs include diuretics, theophylline, converting enzyme inhibitors, calcium channel blockers, indomethacin, and dopamine.
AB - In the neonate, there are a number of age-related differences in drug disposition (bioavailability, distribution, metabolism, and excretion), and these are directly related to the degree of prematurity. This article discusses the use of drugs that are commonly administered to the neonatal patient, with special emphasis given to renal considerations. These drugs include diuretics, theophylline, converting enzyme inhibitors, calcium channel blockers, indomethacin, and dopamine.
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U2 - 10.1016/s0095-5108(18)30486-x
DO - 10.1016/s0095-5108(18)30486-x
M3 - Review article
C2 - 1576772
AN - SCOPUS:0026612326
SN - 0095-5108
VL - 19
SP - 251
EP - 263
JO - Clinics in Perinatology
JF - Clinics in Perinatology
IS - 1
ER -