Dynorphin: A possible modulatory peptide on morphine or β-endorphin analgesia in mouse

Howard J. Friedman, Ming Feng Jen, Jaw Kang Chang, Nancy M. Lee, Horace H. Loh

Research output: Contribution to journalArticlepeer-review

126 Scopus citations

Abstract

Dynorphin-(1-13), but not dynorphin-(1-9) has been shown to have significant effects on opiate and β-endorphin-induced analgesia despite not having any appreciable analgesic activity itself. Dynorphin had no effect on Sandoz FK33824 compound-induced analgesia.

Original languageEnglish (US)
Pages (from-to)357-360
Number of pages4
JournalEuropean Journal of Pharmacology
Volume69
Issue number3
DOIs
StatePublished - Jan 29 1981

Keywords

  • Analgesia
  • Dynorphin
  • Morphine
  • β-Endorphin

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