Effect of butorphanol tartrate on food and water consumption in humans

J. E. Morley, S. Parker, A. S. Levine

Research output: Contribution to journalArticlepeer-review

28 Scopus citations

Abstract

There is much evidence that endogenous opioid peptides are involved in the regulation of food and water intake in a variety of species. We report here that the exogenous opiate agonist, butorphanol tartrate (1 μg/kg), significantly increases food, but not water, intake in normal humans. The major effect on food intake was seen within the first 2 h after the administration of drug. These findings suggest that this drug may be therapeutically useful in patients with cancer anorexia.

Original languageEnglish (US)
Pages (from-to)1175-1178
Number of pages4
JournalAmerican Journal of Clinical Nutrition
Volume42
Issue number6
DOIs
StatePublished - 1985

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