Effect of centrally administered corticotropin releasing factor (CRF) on multiple feeding paradigms

A. S. Levine; Bernetta Rogers; Julie Kneip; Martha Grace; J. E. Morley

doi:10.1016/0028-3908(83)90249-6

Effect of centrally administered corticotropin releasing factor (CRF) on multiple feeding paradigms

A. S. Levine, Bernetta Rogers, Julie Kneip, Martha Grace, J. E. Morley

Medicine - Administration

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Abstract

Recently, a 41-residue corticotropin-releasing factor (CRF) has been characterized from the hypothalamus. In the present study, it was found that this stress-related peptide suppressed feeding induced by a variety of substances including muscimol, norepinephrine, dynorphin and insulin. These data suggest that the corticotropin-releasing factor may represent an important agent in stress-induced anorexia.

Original language	English (US)
Pages (from-to)	337-339
Number of pages	3
Journal	Neuropharmacology
Volume	22
Issue number	3 PART 1
DOIs	https://doi.org/10.1016/0028-3908(83)90249-6
State	Published - Mar 1983

Bibliographical note

Funding Information:
Acknowledgements--We thank Joann Tallman for secretarial assistance. These studies were supported by research funds from the VA Medical Center.

Keywords

CRF
anorexia
dynorphin
feeding
insulin
muscimol
norepinephrine
stress

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abstract = "Recently, a 41-residue corticotropin-releasing factor (CRF) has been characterized from the hypothalamus. In the present study, it was found that this stress-related peptide suppressed feeding induced by a variety of substances including muscimol, norepinephrine, dynorphin and insulin. These data suggest that the corticotropin-releasing factor may represent an important agent in stress-induced anorexia.",

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AU - Grace, Martha

AU - Morley, J. E.

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AB - Recently, a 41-residue corticotropin-releasing factor (CRF) has been characterized from the hypothalamus. In the present study, it was found that this stress-related peptide suppressed feeding induced by a variety of substances including muscimol, norepinephrine, dynorphin and insulin. These data suggest that the corticotropin-releasing factor may represent an important agent in stress-induced anorexia.

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Effect of centrally administered corticotropin releasing factor (CRF) on multiple feeding paradigms

Abstract

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Keywords

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