TY - JOUR
T1 - Effect of spontaneous and mechanical breathing on dynamic lung mechanics in hyaline membrane disease
AU - Mammel, Mark C.
AU - Fisher, Joel B.
AU - Bing, Dennis R.
AU - Gatto, Catherine W.
AU - Boros, Stephen J.
PY - 1990
Y1 - 1990
N2 - We measured then compared the dynamic lung mechanics of spontaneous breaths and mechanical breaths in 9 mechanically ventilated neonates with hyaline membrane disease. All were receiving intermittent mandatory ventilation. All breathed spontaneously between ventilator breaths. Tidal volume, transpulmonary pressure, dynamic lung compliance, airways resistance, and peak inspiratory and peak expiratory gas flows were determined for both the mechanical and the spontaneous breaths. The mechanical breaths consistently had larger tidal volumes, higher transpulmonary pressures, higher airway resistance, and lower lung compliance values (P < 0.05). Peak inspiratory and expiratory gas flows were also higher (P < 0.01) during mechanical breathing. The spontaneous breaths generated by patients and the mechanical breaths generated by mechanical ventilators are different. The lung mechanics measurements of these two different types of breathing should be collected, analyzed, and reported separately. Pediatr Pulmonol 1990; 8:222‐225.
AB - We measured then compared the dynamic lung mechanics of spontaneous breaths and mechanical breaths in 9 mechanically ventilated neonates with hyaline membrane disease. All were receiving intermittent mandatory ventilation. All breathed spontaneously between ventilator breaths. Tidal volume, transpulmonary pressure, dynamic lung compliance, airways resistance, and peak inspiratory and peak expiratory gas flows were determined for both the mechanical and the spontaneous breaths. The mechanical breaths consistently had larger tidal volumes, higher transpulmonary pressures, higher airway resistance, and lower lung compliance values (P < 0.05). Peak inspiratory and expiratory gas flows were also higher (P < 0.01) during mechanical breathing. The spontaneous breaths generated by patients and the mechanical breaths generated by mechanical ventilators are different. The lung mechanics measurements of these two different types of breathing should be collected, analyzed, and reported separately. Pediatr Pulmonol 1990; 8:222‐225.
KW - IMV‐standard pressure preset infant ventilator
KW - dynamic lung compliance
KW - infants with hyaline membrane disease
KW - peak flowrates
KW - pulmonary resistance
KW - tidal volume
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U2 - 10.1002/ppul.1950080403
DO - 10.1002/ppul.1950080403
M3 - Article
C2 - 2371070
AN - SCOPUS:0025061169
SN - 8755-6863
VL - 8
SP - 222
EP - 225
JO - Pediatric pulmonology
JF - Pediatric pulmonology
IS - 4
ER -