Effects of 1 alpha,25-dihydroxycholecalciferol on disuse osteoporosis in the dog: a histomorphometric study.

D. D. Caywood, L. J. Wallace, W. G. Olson, J. B. Stevens

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

Disuse osteoporosis was produced in dogs by immobilization of the left rear limb in a plaster cast. The trabecular bone volume of the calcaneus was then determined following treatment with 1 alpha,25-dihydroxycholecalciferol for 4 weeks with oral dosages of 60 to 240 ng/kg of body weight. The trabecular bone volume percentage of the immobilized calcaneus was in direct relation to the dosage of 1 alpha,25-dihydroxycholecalciferol.

Original languageEnglish (US)
Pages (from-to)89-91
Number of pages3
JournalAmerican journal of veterinary research
Volume40
Issue number1
StatePublished - Jan 1979

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