Effects of Exercise on Plasma Lactate Dehydrogenase and Isoenzyme Activities in Trained and Untrained Rats

Nicholas M. Papadopoulos, Arthur S. Leon, Colin M. Bloor

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

By the combined determination of LDH and isoenzymes in rat plasma, the degree and extent of training required to prevent the marked rise of enzymatic activity associated with exercise was investigated. Training by swimming 1 hr daily for 1-10 weeks provided little or partial protection against severe exercise. Training 4 hr daily for 6-8 weeks prevented the enzymatic changes observed after severe exercise. By isoenzyme analysis the rise of plasma LDH activity was associaed with the kidney, heart, liver, and muscle; they further showed that adaptation to exercise by training varied in the different organs.

Original languageEnglish (US)
Pages (from-to)232-234
Number of pages3
JournalProceedings of the Society for Experimental Biology and Medicine
Volume129
Issue number1
DOIs
StatePublished - Oct 1968

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