TY - JOUR
T1 - Effects of porcine reproductive and respiratory syndrome virus infection on the performance of pregnant gilts and growing pigs
AU - Lewis, Craig R.G.
AU - Ait-Ali, Tahar
AU - Wilson, Alison
AU - Westcott, Dave G.
AU - Frossard, Jean Pierre
AU - Naidu, Brindha
AU - Mellencamp, Marnie A.
AU - Torremorell, Montserrat
AU - Drew, Trevor
AU - Bishop, Stephen C.
AU - Archibald, Alan L.
N1 - Copyright:
Copyright 2011 Elsevier B.V., All rights reserved.
PY - 2010
Y1 - 2010
N2 - This study examined the effects of porcine reproductive and respiratory syndrome virus (PRRSV) infection on (1) pregnant and (2) growing Landrace and crossbred (Large White Pietrain) pigs. First, recently pregnant gilts were spilt into a control and a challenged group, which was inoculated with the PRRSV, and phenotypic effects were recorded. In the Landrace breed, infected gilts had a significantly reduced number of fetuses (8.9 versus 11.8), but there were insufficient data to make the same comparison in crossbred gilts. The Landrace had a smaller suppression of weight gain during pregnancy than the crossbred line [56% (0.66 to 0.29 kg/day) versus 85% (0.45 to 0.07 kg/day) reduction], suggesting greater tolerance of the PRRSV infection. Second, impacts on growing pigs were examined with the same deliberate challenge methodology. Some pigs appeared not to become infected from the initial inoculation, but were possibly subsequently infected by cohorts. However, there were indications of Landrace line resistance in terms of an increased time to seroconvert, with weight gain patterns also suggesting Landrace tolerance. In summary, this study demonstrated that breeds differ consistently in phenotypic impacts of PRRSV infection.
AB - This study examined the effects of porcine reproductive and respiratory syndrome virus (PRRSV) infection on (1) pregnant and (2) growing Landrace and crossbred (Large White Pietrain) pigs. First, recently pregnant gilts were spilt into a control and a challenged group, which was inoculated with the PRRSV, and phenotypic effects were recorded. In the Landrace breed, infected gilts had a significantly reduced number of fetuses (8.9 versus 11.8), but there were insufficient data to make the same comparison in crossbred gilts. The Landrace had a smaller suppression of weight gain during pregnancy than the crossbred line [56% (0.66 to 0.29 kg/day) versus 85% (0.45 to 0.07 kg/day) reduction], suggesting greater tolerance of the PRRSV infection. Second, impacts on growing pigs were examined with the same deliberate challenge methodology. Some pigs appeared not to become infected from the initial inoculation, but were possibly subsequently infected by cohorts. However, there were indications of Landrace line resistance in terms of an increased time to seroconvert, with weight gain patterns also suggesting Landrace tolerance. In summary, this study demonstrated that breeds differ consistently in phenotypic impacts of PRRSV infection.
KW - genetics
KW - host-virus interactions
KW - resistance.
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U2 - 10.1071/AN10023
DO - 10.1071/AN10023
M3 - Article
AN - SCOPUS:77957566138
VL - 50
SP - 890
EP - 896
JO - Animal Production Science
JF - Animal Production Science
SN - 1836-0939
IS - 9
ER -