Effects of Surgical Menopause on Psychological Characteristics and Lipid Levels: The Healthy Women Study

Susan A. Everson, Karen A. Matthews, David S. Guzick, Rena R. Wing, Lewis H. Kuller

Research output: Contribution to journalArticlepeer-review

35 Scopus citations

Abstract

The authors examined the effects of surgical menopause, with or without hormone replacement therapy (HRT), on psychosocial functioning and lipid levels in a population-based study of initially premenopausal women. Within 5 years of study entry, 28 women underwent hysterectomy, with 9 retaining their ovaries and 19 having bilateral salpingo oophorectomy (BSO), and with 173 premenopausal women as a comparison group. Women undergoing hysterectomy reported fewer stress symptoms and a more optimistic attitude at follow-up, whereas BSO cases without HRT had lower mean total high-density lipoprotein (HDL) and HDL2, relative to premenopausal women. Subject to limited power, the authors' findings suggest that surgical menopause among middle-aged women does not lead to negative psychological outcomes but that BSO in the absence of hormone use has significant adverse effects on total HDL and HDL2.

Original languageEnglish (US)
Pages (from-to)435-443
Number of pages9
JournalHealth Psychology
Volume14
Issue number5
DOIs
StatePublished - Sep 1995

Keywords

  • hormone replacement therapy
  • lipid metabolism
  • lipoproteins
  • psychosocial functioning
  • surgiccal menopause

Fingerprint

Dive into the research topics of 'Effects of Surgical Menopause on Psychological Characteristics and Lipid Levels: The Healthy Women Study'. Together they form a unique fingerprint.

Cite this