Encephalopathy, stroke, and myocardial infarction with DMSO use in stem cell transplantation

Alice S. Chen-Plotkin, Keith A. Vossel, Martin A. Samuels, Ming Hui Chen

Research output: Contribution to journalArticlepeer-review

30 Scopus citations

Abstract

Stem cell transplants are established therapy for hematologic and solid tumor malignancies. Known neurological complications of stem cell transplantation include CNS infection, seizures, strokes, metabolic encephalopathy, and hemorrhage. We report two cases of autologous stem cell transplantation complicated by cerebral infarction and myocardial injury. We postulate that the cryopreservative dimethyl sulfoxide may be responsible.

Original languageEnglish (US)
Pages (from-to)859-861
Number of pages3
JournalNeurology
Volume68
Issue number11
DOIs
StatePublished - Mar 2007

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