TY - JOUR
T1 - Engineering of secondary metabolite pathways
AU - Mijts, Benjamin N.
AU - Schmidt-Dannert, Claudia
PY - 2003/12
Y1 - 2003/12
N2 - Nature produces an astonishing wealth of secondary metabolites with important biological functions. To access this diversity of structurally complex chemical compounds for industrial and biomedical applications, cells have been engineered to produce higher levels and/or novel compounds that were previously inaccessible. Recent examples of metabolic and combinatorial engineering illustrate different strategies for the production of secondary metabolites in microbial cells.
AB - Nature produces an astonishing wealth of secondary metabolites with important biological functions. To access this diversity of structurally complex chemical compounds for industrial and biomedical applications, cells have been engineered to produce higher levels and/or novel compounds that were previously inaccessible. Recent examples of metabolic and combinatorial engineering illustrate different strategies for the production of secondary metabolites in microbial cells.
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U2 - 10.1016/j.copbio.2003.09.009
DO - 10.1016/j.copbio.2003.09.009
M3 - Review article
C2 - 14662388
AN - SCOPUS:0344255740
SN - 0958-1669
VL - 14
SP - 597
EP - 602
JO - Current opinion in biotechnology
JF - Current opinion in biotechnology
IS - 6
ER -