TY - JOUR
T1 - Equine proliferative enteropathy - a review of recent developments
AU - Pusterla, N.
AU - Gebhart, C. J.
PY - 2013/7
Y1 - 2013/7
N2 - Equine proliferative enteropathy (EPE) is a disease of foals caused by the obligate intracellular organism Lawsonia intracellularis. This emerging disease affects mainly weanling foals and causes fever, lethargy, peripheral oedema, diarrhoea, colic and weight loss. The diagnosis of EPE may be challenging and relies on the presence of hypoproteinaemia, thickening of segments of the small intestinal wall observed upon abdominal ultrasonography, positive serology and molecular detection of L.intracellularis in faeces. Although the clinical entity, diagnostic approach and treatment of EPE are well established and described, the epidemiology for this disease has remained largely unaddressed. This article focuses on new developments in the field of EPE, including epidemiology, pathophysiology, clinical signs, diagnosis, treatment and prevention.
AB - Equine proliferative enteropathy (EPE) is a disease of foals caused by the obligate intracellular organism Lawsonia intracellularis. This emerging disease affects mainly weanling foals and causes fever, lethargy, peripheral oedema, diarrhoea, colic and weight loss. The diagnosis of EPE may be challenging and relies on the presence of hypoproteinaemia, thickening of segments of the small intestinal wall observed upon abdominal ultrasonography, positive serology and molecular detection of L.intracellularis in faeces. Although the clinical entity, diagnostic approach and treatment of EPE are well established and described, the epidemiology for this disease has remained largely unaddressed. This article focuses on new developments in the field of EPE, including epidemiology, pathophysiology, clinical signs, diagnosis, treatment and prevention.
KW - Clinical management
KW - Equine proliferative enteropathy
KW - Horse
KW - Lawsonia intracellularis
KW - Pathophysiology
UR - http://www.scopus.com/inward/record.url?scp=84878928626&partnerID=8YFLogxK
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U2 - 10.1111/evj.12075
DO - 10.1111/evj.12075
M3 - Review article
C2 - 23662705
AN - SCOPUS:84878928626
SN - 0425-1644
VL - 45
SP - 403
EP - 409
JO - Equine veterinary journal
JF - Equine veterinary journal
IS - 4
ER -