Erythrocyte glutathione and its metabolizing enzymes in bovine urinary bladder cancer

R. K. Dawra; O. P. Sharma; L. Krishna; J. Vaid

doi:10.1016/0304-3835(89)90051-7

Erythrocyte glutathione and its metabolizing enzymes in bovine urinary bladder cancer

R. K. Dawra, O. P. Sharma, L. Krishna, J. Vaid

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Abstract

Glutathione and its metabolizing enzymes were studied in erythrocytes of cattle suffering from urinary bladder cancer and associated hematuria. The concentration of glutathione (GSH) and GSH peroxidase activity were subnormal in the affected animals, whereas activities of GSH reductase and GSH S-transferase were not altered. Decreased GSH and GSH peroxidase are likely to make erythrocytes of the affected animals more susceptible to oxygen-induced injury and the radiomimetic effect of bracken fern.

Original language	English (US)
Pages (from-to)	143-146
Number of pages	4
Journal	Cancer Letters
Volume	48
Issue number	2
DOIs	https://doi.org/10.1016/0304-3835(89)90051-7
State	Published - Nov 30 1989

Keywords

bovine urinary bladder cancer
enzootic bovine hematuria
erythrocytes
glutathione
glutathione peroxidase

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title = "Erythrocyte glutathione and its metabolizing enzymes in bovine urinary bladder cancer",

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AU - Dawra, R. K.

AU - Sharma, O. P.

AU - Krishna, L.

AU - Vaid, J.

PY - 1989/11/30

Y1 - 1989/11/30

N2 - Glutathione and its metabolizing enzymes were studied in erythrocytes of cattle suffering from urinary bladder cancer and associated hematuria. The concentration of glutathione (GSH) and GSH peroxidase activity were subnormal in the affected animals, whereas activities of GSH reductase and GSH S-transferase were not altered. Decreased GSH and GSH peroxidase are likely to make erythrocytes of the affected animals more susceptible to oxygen-induced injury and the radiomimetic effect of bracken fern.

AB - Glutathione and its metabolizing enzymes were studied in erythrocytes of cattle suffering from urinary bladder cancer and associated hematuria. The concentration of glutathione (GSH) and GSH peroxidase activity were subnormal in the affected animals, whereas activities of GSH reductase and GSH S-transferase were not altered. Decreased GSH and GSH peroxidase are likely to make erythrocytes of the affected animals more susceptible to oxygen-induced injury and the radiomimetic effect of bracken fern.

KW - bovine urinary bladder cancer

KW - enzootic bovine hematuria

KW - erythrocytes

KW - glutathione

KW - glutathione peroxidase

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ER -

Erythrocyte glutathione and its metabolizing enzymes in bovine urinary bladder cancer

Abstract

Keywords

UN SDGs

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