TY - JOUR
T1 - Escherichia coli sequence type ST131 as an emerging fluoroquinolone- resistant uropathogen among renal transplant recipients
AU - Johnson, James R.
AU - Johnston, Brian
AU - Clabots, Connie
AU - Kuskowski, Michael A.
AU - Pendyala, Swaroop
AU - DeBroy, Chitrita
AU - Nowicki, Bogdan
AU - Rice, James
PY - 2010/1
Y1 - 2010/1
N2 - Among 40 Escherichia coli urine isolates from renal transplant recipients (Galveston, TX, 2003 to 2005), sequence type ST131 (O25:H4) was highly prevalent (representing 35% of isolates overall and 60% of fluoroquinolone-resistant isolates), virulent appearing, antimicrobial resistant (but extended-spectrum- cephalosporin susceptible), and associated with black race. Pulsotypes were diverse; some were linked to other locales. ST131 emerged significantly during the study period. These findings suggest that E. coli ST131 may constitute an important new multidrug-resistant threat to renal transplant recipients.
AB - Among 40 Escherichia coli urine isolates from renal transplant recipients (Galveston, TX, 2003 to 2005), sequence type ST131 (O25:H4) was highly prevalent (representing 35% of isolates overall and 60% of fluoroquinolone-resistant isolates), virulent appearing, antimicrobial resistant (but extended-spectrum- cephalosporin susceptible), and associated with black race. Pulsotypes were diverse; some were linked to other locales. ST131 emerged significantly during the study period. These findings suggest that E. coli ST131 may constitute an important new multidrug-resistant threat to renal transplant recipients.
UR - http://www.scopus.com/inward/record.url?scp=73849102484&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=73849102484&partnerID=8YFLogxK
U2 - 10.1128/AAC.01089-09
DO - 10.1128/AAC.01089-09
M3 - Article
C2 - 19917759
AN - SCOPUS:73849102484
SN - 0066-4804
VL - 54
SP - 546
EP - 550
JO - Antimicrobial agents and chemotherapy
JF - Antimicrobial agents and chemotherapy
IS - 1
ER -