Estimatien of Infectious Potential of Blood Containing Human Immunodeficiency Virus

John E Connett; F. S. Rhame; J. Thomas; Chap T Le

doi:10.1002/bimj.4710320703

Estimatien of Infectious Potential of Blood Containing Human Immunodeficiency Virus

John E Connett, F. S. Rhame, J. Thomas, Chap T Le

Biostatistics

Research output: Contribution to journal › Article › peer-review

Abstract

A method is described for estimating the probability that transfusion of a given quantity of blood from an AIDS‐infected donor will result in infection in the recipient. The method is based on maximum likelihood, and requires the assumption that individual viruses act independently in causing infection. Results of simulations indicate that the resulting estimates have low bias. The method is applicable to a wide variety of other problems.

Original language	English (US)
Pages (from-to)	781-789
Number of pages	9
Journal	Biometrical Journal
Volume	32
Issue number	7
DOIs	https://doi.org/10.1002/bimj.4710320703
State	Published - 1990

Keywords

AIDS
HIV infection
Maximum likelihood

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access

10.1002/bimj.4710320703

OpenUrl availability

Full text

Cite this

@article{e35dc0b3029d40fc92a2bd03f4063a5b,

title = "Estimatien of Infectious Potential of Blood Containing Human Immunodeficiency Virus",

abstract = "A method is described for estimating the probability that transfusion of a given quantity of blood from an AIDS‐infected donor will result in infection in the recipient. The method is based on maximum likelihood, and requires the assumption that individual viruses act independently in causing infection. Results of simulations indicate that the resulting estimates have low bias. The method is applicable to a wide variety of other problems.",

keywords = "AIDS, HIV infection, Maximum likelihood",

author = "Connett, {John E} and Rhame, {F. S.} and J. Thomas and Le, {Chap T}",

year = "1990",

doi = "10.1002/bimj.4710320703",

language = "English (US)",

volume = "32",

pages = "781--789",

journal = "Biometrical Journal",

issn = "0323-3847",

publisher = "Wiley-VCH Verlag",

number = "7",

}

TY - JOUR

T1 - Estimatien of Infectious Potential of Blood Containing Human Immunodeficiency Virus

AU - Connett, John E

AU - Rhame, F. S.

AU - Thomas, J.

AU - Le, Chap T

PY - 1990

Y1 - 1990

N2 - A method is described for estimating the probability that transfusion of a given quantity of blood from an AIDS‐infected donor will result in infection in the recipient. The method is based on maximum likelihood, and requires the assumption that individual viruses act independently in causing infection. Results of simulations indicate that the resulting estimates have low bias. The method is applicable to a wide variety of other problems.

AB - A method is described for estimating the probability that transfusion of a given quantity of blood from an AIDS‐infected donor will result in infection in the recipient. The method is based on maximum likelihood, and requires the assumption that individual viruses act independently in causing infection. Results of simulations indicate that the resulting estimates have low bias. The method is applicable to a wide variety of other problems.

KW - AIDS

KW - HIV infection

KW - Maximum likelihood

UR - http://www.scopus.com/inward/record.url?scp=84982037249&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84982037249&partnerID=8YFLogxK

U2 - 10.1002/bimj.4710320703

DO - 10.1002/bimj.4710320703

M3 - Article

AN - SCOPUS:84982037249

SN - 0323-3847

VL - 32

SP - 781

EP - 789

JO - Biometrical Journal

JF - Biometrical Journal

IS - 7

ER -

Estimatien of Infectious Potential of Blood Containing Human Immunodeficiency Virus

Abstract

Keywords

UN SDGs

Access

OpenUrl availability

Other files and links

Fingerprint

Cite this