Estimation of the sensitivity and specificity of the agar gel immunodiffusion test for bovine leukemia virus: 1,296 cases (1982-1989).

D. R. Monke, R. F. Rohde, W. D. Hueston, R. J. Milburn

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14 Scopus citations

Abstract

A retrospective study of the results of 12,549 agar gel immunodiffusion tests for bovine leukemia virus, conducted on 1,296 dairy bulls over an 8-year period, was performed to estimate the sensitivity and specificity of the test. The number of tests performed on each bull ranged from 5 to 35, with a mean of 9.7 tests per bull. Bulls were categorized by their agar gel immunodiffusion test responses; 1,069 (82.5%) were noninfected and 227 (17.5%) were infected. Eighteen false-positive results were reported from the noninfected bulls. Test specificity was estimated to be 99.8%. Thirty-one false-negative results were reported from the infected bulls. Test sensitivity was estimated to be 98.5%. Fifty-six bulls had 1 or more positive responses when less than 6 months old. In 26 (46%), these results were thought to be attributable to colostral immunity.

Original languageEnglish (US)
Pages (from-to)2001-2004
Number of pages4
JournalJournal of the American Veterinary Medical Association
Volume200
Issue number12
StatePublished - Jun 15 1992

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