Abstract
Chronic Hepatitis B (HBV) is the most important cause of liver disease worldwide. There is a need for low-cost tests to aid in diagnosis and management of HBV infection in resource-limited settings. We evaluated the utility of several rapid diagnostic tests (RDT) in three different continents (Europe, South America, Africa). The HBsAg RDT showed optimal sensitivity and specificity. The anti-HBeAb RDT showed acceptable sensitivity and excellent specificity. Our results suggest that these RDTs could be used for screening and management of HBV.
Original language | English (US) |
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Article number | 98 |
Journal | Annals of global health |
Volume | 85 |
Issue number | 1 |
DOIs | |
State | Published - 2019 |
Bibliographical note
Funding Information:This work was supported by the Doris Duke International Clinical Research Fellowship Program at the University of Minnesota to JL, the Robert Wood Johnson Foundation, AFMDP, Mitialto Foundation and NIH-NCI R21 CA215883-01A1 all to JDD. Funding sponsors had no role in the production of this manuscript.
Funding Information:
This work was supported by the Doris Duke International Clinical Research Fellowship Program at the University of Minnesota to JL, the Robert Wood Johnson Foundation, AFMDP, Mitialto Foundation and NIH-NCIR21 CA215883-01A1 all to JDD. Funding sponsors had no role in the production of this manuscript.
Publisher Copyright:
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