Evaluation of the biofragmentable anastomotic ring following preoperative irradiation to the rectosigmoid in dogs

A. Don Smith, Melvin P. Bubrick, Steven T. Mestitz, F. Michael Crouch, Gary R. Johnston, Daniel A. Feeney, Robert L. Strom, John W. Maney

Research output: Contribution to journalArticlepeer-review

20 Scopus citations

Abstract

An animal study was done to evaluate the safety of a sutureless colorectal anastomosis in irradiated bowel. Forty mongrel dogs received preoperative radiation with 5000 rads and then underwent a low anterior resection and anastomosis using either the EEA-31 stapling device, a two-layer handsewn technique, or the biofragmentable anastomotic ring (BAR) 31-1.5 mm and BAR 31-2.0 mm devices. The anastomoses were then evaluated for early and late anastomotic healing and leaks. The results show four radiographic (three clinical) leaks (P<.05) in the BAR 31-1.5 mm group and one radiographic leak in the handsewn group. No leaks were detected in the EEA or BAR 31-2.0 mm groups. Results indicate that all three techniques can be done safely with this dose of radiation, and gap size (1.5 mm vs. 2.0 mm) is of critical importance when performing a BAR anastomosis in irradiated bowel.

Original languageEnglish (US)
Pages (from-to)5-9
Number of pages5
JournalDiseases of the Colon & Rectum
Volume31
Issue number1
DOIs
StatePublished - Jan 1 1988

Keywords

  • Anastomotic dehiscence
  • Biofragmentable anastomotic ring
  • Colorectal anastomosis
  • Preoperative irradiation

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