Evolution of DNA and RNA as catalysts for chemical reactions

Andres Jäschke, Burckhard Seelig

Research output: Contribution to journalReview articlepeer-review

46 Scopus citations

Abstract

In vitro selection from combinatorial nucleic acid libraries has provided new RNA and DNA molecules that have catalytic properties. Catalyzed reactions now go far beyond self-modifying reactions of nucleic acid molecules. The future application of in vitro selected RNA and DNA catalysts in bioorganic synthesis appears promising.

Original languageEnglish (US)
Pages (from-to)257-262
Number of pages6
JournalCurrent opinion in chemical biology
Volume4
Issue number3
DOIs
StatePublished - Jun 1 2000

Bibliographical note

Funding Information:
Work in the author’s laboratory is supported by the Deutsche Forschungsgemeinschaft (DFG) and by the Bundesministerium für Bildung und Forschung (BMBF).

Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.

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