Excremental studies in human neonates. Identification of zinc coproporphyrin as a marker for meconium

Glenn R. Gourley, Bill Kreamer, Richard Arend

Research output: Contribution to journalArticlepeer-review

29 Scopus citations

Abstract

Zinc coproporphyrin, isomers I and III (I:III ratio, approximately 8:1), was identified in human meconium using high-performance liquid chromatography, ultraviolet-visible absorbance spectroscopy, and emission fluorescence spectroscopy. The high levels of zinc coproporphyrin in the first stools of life decrease steadily as meconium is evacuated and reach a plateau at comparatively negligible levels after complete evacuation of meconium. Zinc coproporphyrin can be used as a marker for human meconium.

Original languageEnglish (US)
Pages (from-to)1705-1709
Number of pages5
JournalGastroenterology
Volume99
Issue number6
DOIs
StatePublished - Dec 1990

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