Expanding the use of magnetic resonance in the assessment of tumor response to therapy: Workshop report

Jeffrey Evelhoch, Michael Garwood, Daniel Vigneron, Michael Knopp, Daniel Sullivan, Anne Menkens, Laurence Clarke, Guoying Liu

Research output: Contribution to journalArticlepeer-review

84 Scopus citations

Abstract

Although dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) and magnetic resonance spectroscopy (MRS) have great potential to provide routine assessment of cancer treatment response, their widespread application has been hampered by a lack of standards for use. Thus, the National Cancer Institute convened a workshop to assess developments and applications of these methods, develop standards for methodology, and engage relevant partners (drug and device industries, researchers, clinicians, and government) to encourage sharing of data and methodologies. Consensus recommendations were reached for DCE-MRI methodologies and the focus for initial multicenter trials of MRS. In this meeting report, we outline the presentations, the topics discussed, the ongoing challenges identified, and the recommendations made by workshop participants for the use of DCE-MRI and 1H MRS in the clinical assessment of antitumor therapies.

Original languageEnglish (US)
Pages (from-to)7041-7044
Number of pages4
JournalCancer Research
Volume65
Issue number16
DOIs
StatePublished - Aug 15 2005

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