Experimental models for the study of chronoimmunomodulation (rhythms of the springtail Folsomia candida, Collembola: Isotomidae).

M. D. Marques, G. Cornélissen, L. K. Cutkomp, F. Halberg, N. Marques

Research output: Contribution to journalArticlepeer-review

Abstract

A third-generation cephalosporine, cefodizime, was tested in two experiments on the springtail, Folsomia candida, used as a model of infradian rhythmicity. Any effect on ecdysis (molt), oviposition and oviproduction was sought for 6, 20 or 60 ng of cefodizime administered with brewer's yeast every other day, as compared to controls given only the yeast. Results indicate that a 20-ng dose of cefodizime on alternate days may shorten an infradian period (of molt) in the springtail.

Original languageEnglish (US)
Pages (from-to)183-189
Number of pages7
JournalChronobiologia
Volume15
Issue number1-2
StatePublished - Jan 1 1988

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